HORDB

ID: hor006610
Uniprot ID: O73812
Protein name: GnRH-associated peptide 1
Gene name: gnrh1
Organism: Morone saxatilis (Striped bass) (Perca saxatilis)
Family: GnRH family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Morone (genus), Moronidae (family), Eupercaria incertae sedis, Eupercaria, Percomorphaceae, Euacanthomorphacea, Acanthomorphata, Ctenosquamata, Eurypterygia, Neoteleostei, Euteleosteomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Sequence: ELDGLSETLGNQIVGGFPHVETPCRVLGCAVESPFPKIYRMKGFLDAVTDRENGPRTYKK
Length: 60
Propeptide: MAPQTFALWLLLVGTLLGQGCCQHWSYGLSPGGKRELDGLSETLGNQIVGGFPHVETPCRVLGCAVESPFPKIYRMKGFLDAVTDRENGPRTYKK
Signal peptide: MAPQTFALWLLLVGTLLGQGCC
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor006610_AF2.pdb

hor006610_ESM.pdb

Mass:	769114	Formula:	C294H465N81O88S3
Absent amino acids:	W	Common amino acids:	G
pI:	7.25	Basic residues:	9
Polar residues:	19	Hydrophobic residues:	17
Hydrophobicity:	-42	Boman Index:	-10424
Half-Life:	1 hour	Half-Life Yeast:	30 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	73
Instability Index:	1642.33	Extinction Coefficient cystines:	3105
Absorbance 280nm:	52.63

PubMed ID: 9845669
Title: Multiple GnRHs present in a teleost species are encoded by separate genes: analysis of the sbGnRH and cGnRH-II genes from the striped bass, Morone saxatilis.